Napoli have been hit with another painful setback, as Franck Zambo Anguissa has picked up a high-grade lesion to the biceps femoris in his left thigh while on international duty with Cameroon. The injury, confirmed after medical tests at Pineta Grande Hospital, is expected to keep him out for months, which sadly means he’ll also miss the upcoming Africa Cup of Nations. This was confirmed by Fabrizio Romano via his official X account.
View the post below:
🚨 Napoli report announce high grade lesion for Franck Zambo Anguissa and several months out.
— Fabrizio Romano (@FabrizioRomano) November 13, 2025
Cameroon midfielder, expected to miss the AFCON as well. ❌🇨🇲
One more major blow for Napoli after De Bruyne and Lukaku. pic.twitter.com/uyKYnpl1L3
It couldn’t really come at a worse time, honestly. Anguissa was flying high lately, having just been voted Napoli’s Player of the Month for October. He was in fine form, scoring three important goals against Genoa, Inter Milan, and Lecce, all while running the midfield with his usual mix of strength, composure, and creativity. It really looked like the 29-year-old had found his best rhythm again.
But now, after such a bright spell, he’s facing a long, difficult recovery road. The club confirmed via their official X account he’s already started his rehabilitation process, though there’s no clear timeline for his return yet. One thing’s sure: his absence will be felt deeply in Napoli’s engine room.
View the post below:
Bollettino medico | Le condizioni di Anguissa 👇https://t.co/QeL3ZIm1e5 pic.twitter.com/j4VKeuMowF
— Official SSC Napoli (@sscnapoli) November 13, 2025
For a side already dealing with their share of injuries this season, this feels like another heavy punch to the team. With players like Kelvin De Bruyne being sidelined due to injury, as reported earlier by Softfootball and Romelu Lukaku earlier in the campaign, losing Anguissa adds even more pressure on Napoli’s midfield depth.

The blow isn’t just for Napoli but for Cameroon also, who are fighting for a spot in the World Cup, as reported by Softfootball. Anguissa’s leadership and presence have always been vital for the Indomitable Lions, and now they’ll have to head into AFCON and also play the rest of the World Cup playoff without one of their most trusted midfield generals.
It’s a harsh twist for a player who’d just rediscovered his spark. But if there’s something everyone knows about Anguissa, it’s his resilience. He’s not the type to give up easily; expect him to fight his way back, stronger and hungrier than before.
