There’s something special brewing in Seville this Tuesday night as Real Betis welcome Atletico Madrid to the Estadio de La Cartuja for a pivotal Matchday 10 encounter. Both sides are level on 16 points, sitting fifth and sixth, respectively, and while it’s still early in the season, this feels like a match that could shape their European hopes.
For Atletico Madrid, the timing couldn’t be trickier. Just days ago, they were humbled 4–0 by Arsenal in the UEFA Champions League, as reported by Softfootball. Diego Simeone’s men looked lost that night, and the coach will expect a fiery response in Seville.

Julian Alvarez, who’s been sensational with eight goals and three assists, could be key once again. As reported by Softfootball, Pep Guardiola recently spoke about the Argentine forward, saying that Alvarez deserved to play more, and he’s surely proving that now.
Meanwhile, Manuel Pellegrini’s Real Betis are quietly flying. They battled to a 2–2 draw with Villarreal, then ground out a 0–0 away at Genk in the Europa League—stretching their unbeaten run to eight matches. Betis look confident, and their home form has been superb, with just one defeat in their last twelve La Liga home fixtures.

Team News
Real Betis: Isco remains out with a fractured fibula. Antony, in good touch with three goals, will likely start on the right. Amrabat could return after missing midweek action.
Atletico Madrid: Johnny Cardoso is doubtful, but Koke, Oblak, and Gimenez are ready to go. Simeone might not change much tactically despite that Arsenal defeat.

Possible Lineups
Real Betis (4-2-3-1): Valles; Ruibal, Bartra, Gómez, Rodríguez; Altimira, Deossa; Antony, Lo Celso, Riquelme; Bakambu.
Atletico Madrid (4-4-2): Oblak; Llorente, Gimenez, Le Normand, Hancko; Simeone, Barrios, Koke, Gonzalez; Sorloth, Alvarez.
Real Betis posted on their official X account to build excitement for their LaLiga home match against Atlético Madrid, highlighting the emotional return to familiar grounds after recent away fixtures.
Two days to be at home again 🫶#RealBetisAtleti pic.twitter.com/cyjGbrUsFR
— Real Betis Balompié (@RealBetis_en) October 25, 2025
Softfootball’s Prediction
Betis have not lost in their last eight and look sharp at home. Atletico’s away form of no wins in six remains a concern. Expect intensity, maybe a bit of chaos. Betis might just snatch it.
Prediction: Real Betis 2–1 Atletico Madrid.
